Getting started with the PhysiCell model

To start working with a model, you first need to open it. To do this, double-click on or right-click on and in the drop-down list, click LMB on icon_opened_folder Open.

After this, a window will appear in the upper left part of the screen in which you can create a model.

At the top of this window you can see a toolbar that is used to build a PhysiCell model.

You can select a particular tool by clicking on the corresponding icon. A description of each tool is provided below.

Elements of the toolbar used when working with PhysiCell models
Designation	Description
	Selecting an element in a diagram
	Cell type
	Substrate
	Event
	Note
	Secretion/Consumption
	Chemotaxis
	Interaction
	Transformation

The main participants of the PhysiCell model are cells of various types ( icon_cell_definition ) and substrates ( icon_substrate ).

There are 4 types of interactions possible between them:

Secretion/Consumption (): secretion/consumption of a particular substrate by a cell.
Chemotaxis (): movement of a cell towards or away from a specific substrate.
Interaction (): the effect of cells of one type on cells of another type,
Transformation (): transformation of cells of one type into cells of another type.